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Millions Share a Deadly Genetic Heart Risk. This Experimental Drug Could Be a Game Changer
A staggering number of people worldwide are unknowingly at risk for a life-threatening cardiovascular condition, as millions carry the genetic predisposition that increases their chances of developing premature heart disease.
Researchers have now discovered that an experimental drug has shown promising results in combating this deadly genetic risk, offering hope for those affected by this silent killer.
The study, published today in the Journal of Cardiovascular Research, highlights the alarming prevalence of a specific gene mutation that is linked to a significantly increased risk of developing coronary artery disease (CAD) and cardiomyopathy, two devastating cardiovascular conditions that can lead to heart failure, arrhythmias, and even death.
According to the data, nearly 1 in every 10 people worldwide carries this genetic mutation, making it a major public health concern.
The experimental drug, dubbed siRNA-02, has been found to effectively reduce triglyceride levels in patients with high cholesterol, which is often an early sign of developing CAD. This breakthrough could potentially revolutionize the treatment and management of cardiovascular disease.
siRNA-02 works by targeting the mutated gene responsible for this increased risk and has shown impressive results in trials conducted on patients with familial hypercholesterolemia (FH), a rare genetic disorder that causes extremely high levels of cholesterol.
The potential implications are immense. With millions carrying this deadly genetic risk, it is crucial to develop effective treatments that address the root cause of the condition, rather than just managing its symptoms.
siRNA-02 offers hope for those affected by this silent killer, and further research will be essential in refining its efficacy and exploring its potential as a game-changer for cardiovascular health.
Source: https://gizmodo.com/millions-share-a-deadly-genetic-heart-risk-this-experimental-drug-could-be-a-game-changer-2000582742
